Hmmm... How about a 7-day Regent cruise from Vancouver to Seward, then two weeks by car and plane so you can visit Denali and other interior sites, and then a 7-day Regent cruise from Seward back to Vancouver -- that sounds pretty "best" to me! ;)

Joking aside, the one significant shortcoming to Regent's Alaska itineraries, to me, is that they don't go to Glacier Bay. We were contemplating flying there after our cruise next month to do it on our own, but there were too many other things for us to see on this first visit to Alaska, and because that side trip would add several days, we had to drop the idea. Otherwise, having cruised with Regent multiple times before, I fully expect the cruise experience to be top notch -- and the free and reduced cost excursions this year make a huge difference in allowing us to see and do more than we'd have done paying full cost for the expensive Alaska excursions.

-- Eric