Looking at the email again from Regent, it only specifies Puerto Qutezal. We are there from 7am to 3pm. We chose the Macadamia Nut farm excurstion, but then decided we'd rather do Ancient Antigua and city tour, which we are waitlisted for. So am wondering.....maybe Ngaire you would have some input on this....is the medication reallly necessary? Are there other areas on this trip that might be a concern? Is anyone else planning on getting the medication and taking it? Mosquitos love me, but if I am only outside during the day, use a good repellant and don't open the balcony door or go out on the balcony the night before, and when we leave is that enough?