Ngaire, thanks. I have only found the flight from Copenhagen. The reason might be as simple as no customs/immigration in Kangerlussuaq so you can only get there from a domestic airport such as Copenhagen. I am researching other options such as flight to east coast of Greenland and then domestic flight to Kangerlussuaq.

I have not liked ff options so far and paying for tickets is expensive. Silversea even at $2000 per person may be best way to do air.

BTW, Nome is only 1.5 hour flight from Anchorage so not too bad on connections.